My biggest concern is lymphoma. I am being seen by my primary, and endocrinologist due to a thyroid nodule, and a neurologist. I’m trying to educate myself to help find answers. I’ve tried researching elevated B12 and the only things I could find said either Hepatitis or some cancers. My Hep tests (and liver enzymes) are negative/normal ranges. These labs were ordered by my neurologist because I currently have an Idiopathic Autonomic Nervous System Disorder due to sensory loss in feet and ankles according to him. (I won’t see him till after first of year) Other symptoms are low BP; bad itchy skin – lower legs, behind knees, perimeter of armpits year round, rest of torso in winter months, loss of appetite, fatigue, pain beneath/behind collarbones (for @ 6 months). Also have a solid nodule (was complex until after FNA) on thyroid along with smaller cystic nodules. Do not have Hashimoto’s antibodies. Have had an enlarged inguinal lymph – right side – for over 1 year, and for at least a week, enlarged lymph node right side – above voice box and under tongue.
There are some from 3 months ago listed for comparison reasons.
Test – 9/26/08 – 12/02/08 (ref value)
WBC – 9.32 – 8.4 (4.0-11.0 k/uL)
RBC – 4.49 – 4.59 (4.2-5.4 M/uL)
HGB – 14.4 – 15.1 (12.0-16.0 g/dL)
HCT – 43.1 – 44.1 (37-47%)
MCV – 96.0 – 96.1 (80-100 fL)
MCH – 32.1 – 32.9 (27-34 pG)
MCHC – 33.4 – 34.2 (32-36 g/dL)
PLT – 243 – 235 (150-400 k/uL)
RDW-CV -12.4 – 12.6 (11.7-15.0%)
MPV – 10.9 – 11.6 (H) (7.3-11.1 fL)
Neutrophil 63.1 – 58.7 (40-70%)
Abs Neutrophil 5.88 – 9.93 (1.8-7.7 K/uL)
Lymphocyte 23.5 – 28.6 (22-44%)
Abs Lymphocyte 2.19 – 2.40 (1.0-4.0 k/uL)
Monocyte 9.5 (H) – 7.9 (H) (0-7.0%)
Abs Monocyte 0.89 (H) – .66 (0-.08 K/uL)
Eosinophil 2.9 – 3.8 (0-4%)
Abs Eosinophil .27 – .32 (0-0.4 k/uL)
Basophil 1.0 – 1.0 (0-1%)
Abs Basophil .09 – .08 (0-0.2 K/uL)
Misc Labs 12/08 for reference
ANA by EIA – 1.7 (H) (low: <1.5 OD)
(Anti-SM, Anti-RNP, Anti-SSA, Anti-SSB, Anti-Jo-1, Anti-SCL-70 – all negative)
Vitamin B12 – 710 (H) (221-700pg/mL)
Hep B Core Ab, total – Neg
Hep C Antibody IA – Neg
HBsAg – Neg
HepB Surface Ab Qual – Neg
HIV 1 & 2 Ab EIA – Non Reactive
There is a high incident of cancer in my family.
Father’s side:
My grandfather and 4 of his brothers had cancer.
GF – prostate, Gr.Unc.1 – Thyroid, GU2 – bladder, GU3 – prostate
Reason to believe Great Grandfather had cancer as well. He committed suicied in 1928 due to “health reasons”
Cousin – recently passed away from an aggressive leukimia
Mother’s side:
Mother has CLL, also a breast cancer survivor, Great Grandmother – stomach cancer.
Would appreciate any insight into all this.
I tried answering the responses, and this is the only way I found to do it. Don’t know the ages of diagnosis, other than my mother. Both CLL and Breast Cancer were under 50 years old. I mention lymphoma because of the thyroid nodule. According to the National Cancer Society – because we have a family member that had a thyroid cancer, and because my father also has a multi-nodular goiter – I am at an increased risk of developing thyroid lymphoma. If the nodes don’t go down by the time I see my neuro for follow up – I will ask about biopsy. From what I understand, that is the only true way to test for lymphoma. I will be getting tested this coming Monday – EMG, QSRT, Tilt table and skin biopsies (looking for nerve damage).My sister also has a low BP problem, and mine has been like this for a few years – regardless of my fluid and salt intake. That is in part why the neuro tests.
Auto-immune disorders also run high on dad’s side, including me – I have morphea scleroderma.
Thank you!